Nixcof (100mg+1.1mg+14mg/5ml) Syrup

Composition

Each 5 ml syrup contains-

• Gualfonosln BP 100 mg
• Levomenthol BP 1.1 mg
• Diphenhydramine Hydrochlorldo BP 14 mg

Dosage & Administration:

Adults:

• General: 2 teaspoonfuls (tsf) of syrup 4 times a day.
• Night-time cough relief: 2 tsf at bedtime followed by 2 tsf every 6 hours.
• Hepatic dysfunction: Caution is advised for subjects with moderate to severe hepatic dysfunction.

Children:

• Aged 12 years and over 2 tsf 4 times a day. For night-time cough relief, 2 tsf at bedtime followed by 2 tsf every 6 hours.
• Aged under 12 years: Safety and efficacy are not established.

Renal dysfunction: Caution is advised for subjects with moderate to severe renal dysfunction.

• Not recommended for children under 12 years.

Overdose Effects

• Guaifenesin in excess may cause renal calculi. Treatment should be symptomatic and supportive.

Side Effects:

Dizziness, Drowsiness, Dryness in mouth, Difficulty in paying attention, Fatigue, Headache, Sedation, Unsteadiness, Impaired coordination, Epigastric pain, Increased bronchial secretions, Dry mucous membrane, Constipation, Euphoria (feeling of intense excitement and happiness), Abnormality of voluntary movements, Discomfort when urinating, Hypotension (low blood pressure), Double vision, Diaphoresis, Erectile dysfunction, Early menstrual periods, Decreased appetite, Allergic sensitization, Photosensitivity

Drug Interactions

• This may potentiate the effects of alcohol, codeine, antihistamines, and other CNS depressants. Anticholinergic effects may be potentiated by psychotropic drugs and atropine, leading to tachycardia, dry mouth, gastrointestinal disturbances, urinary retention, and headache.
• Should not be used in individuals who have been treated with MAOIs within the last two weeks.

Contraindications

• Known hypersensitivity to any components of the product.

Pregnancy and Lactation

• Care should be taken during pregnancy. No adverse effects have been associated with the human fetus or suckling infant.

Precautions & Warnings

• Avoid using for persistent or chronic cough, such as occurs with asthma, or where cough is accompanied by excessive secretion.
• May impair the ability to drive or operate machinery.
• Caution in patients with narrow-angle glaucoma or symptomatic prostatic hypertrophy.
• Avoid alcohol consumption.
• The medication can be taken with or without food.
• Always follow the instructions of your physician or the product label.
• Inform your doctor about any other medications you are taking to avoid interactions.

Storage Conditions

• Store at a temperature not exceeding 30°C in a dry place.
• Protect from light and moisture.
• Keep out of reach of children.